Juhyuk Park*, Ji Wang*, Webster Guan*, Lars A. Gjesteby, Dylan Pollack, Lee Kamentsky, Nicholas B. Evans, Jeffrey Stirman, Xinyi Gu, Chuanxi Zhao, Slayton Marx, Minyoung E. Kim, Seo Woo Choi, Michael Snyder, David Chavez, Clover Su, Yuxuan Tian, Chang Sin Park, Qiangge Zhang, Dae Hee Yun, Mira Moukheiber, Guoping Feng, X. William Yang, C. Dirk Keene, Patrick R. Hof, Satrajit S. Ghosh, Matthew P. Frosh, Laura J. Brattain, Kwanghun Chung†", “Integrated platform for multi-scale molecular imaging and phenotyping of the human brain” , Science, 2024  

Dae Hee Yun*, Young-Gyun Park*, Jae Hun Cho, Lee Kamentsky, Nicholas B. Evans, Nicholas DiNapoli, Katherine Xie, Seo Woo Choi, Alexandre Albanese, Yuxuan Tian, Chang Ho Sohn, Qiangge Zhang, Minyoung E. Kim, Justin Swaney, Webster Guan, Juhyuk Park, Gabi Drummond, Heejin Choi, Luzdary Ruelas, Guoping Feng, Kwanghun Chung†, “Universal strategy for volumetric single-cell processing and its demonstration in rapid and scalable organ-scale molecular phenotyping“, 2024, in revision

Dylan Pollack, Lars A. Gjesteby, Michael Snyder, David Chavez, Lee Kamentsky, Kwanghun Chung**, Laura J. Brattain*, “Axon centerline detection using topologically-aware 3D U-Nets”, IEEE Engineering In Medicine & Biology Society (EMBC)      

Benjamin Fenelon, Lars Gjesteby, Webster Guan, Juhyuk Park, Kwanghun Chung, and Laura Brattain, “A Scalable Inference Pipeline for 3D Axon Tracing Algorithms”, 2022 IEEE High Performance Extreme Computing Conference (HPEC)      

Jiho Shin†, Hyunseok Kim†, Suresh Sundaram†, Junseok Jeong†, Celesta Chang, Kuangye Lu, Sungkyu Kim, Jun Min Suh, Kiseok Kim, Yunpeng Liu, Kuan Qiao, Bo-In Park, Yeongin Kim, Doeon Lee, Jaeyong Lee, Justin S. Kim, Haneol Lee, Hanwool Yeon, Hyun S. Kum, Sang-Hoon Bae, Kyusang Lee*, Kwanghun Chung†, Young Joon Hong*, Abdallah Ougazzaden*, and Jeehwan Kim*, “Vertical full-color micro-LEDs via 2D material-based layer transfer”, Nature, 2023, 614, 81-87      

Douglas S. Richardson†, Webster Guan, Katsuhiko Matsumoto, Chenchen Pan, Kwanghun Chung, Ali Ertürk, Hiroki R. Ueda, and Jeff W. Lichtman, "Tissue Clearing", Nature Reviews Methods Primers, 2022, DOI: 10.1038/s43586-021-00080-9        

Rodrigo Muñoz-Castañeda, Brian Zingg, Katherine S Matho, Xiaoyin Chen, Quanxin Wang, Nicholas N Foster, Anan Li, Arun Narasimhan, Karla E Hirokawa, Bingxing Huo, Samik Bannerjee, Laura Korobkova, Chris Sin Park, Young-Gyun Park, Michael S Bienkowski, Uree Chon, Diek W Wheeler, Xiangning Li, Yun Wang, Maitham Naeemi, Peng Xie, Lijuan Liu, Kathleen Kelly, Xu An, Sarojini M Attili, Ian Bowman, Anastasiia Bludova, Ali Cetin, Liya Ding, Rhonda Drewes, Florence D’Orazi, Corey Elowsky, Stephan Fischer, William Galbavy, Lei Gao, Jesse Gillis, Peter A Groblewski, Lin Gou, Joel D Hahn, Joshua T Hatfield, Houri Hintiryan, Junxiang Jason Huang, Hideki Kondo, Xiuli Kuang, Philip Lesnar, Xu Li, Yaoyao Li, Mengkuan Lin, Darrick Lo, Judith Mizrachi, Stephanie Mok, Philip R Nicovich, Ramesh Palaniswamy, Jason Palmer, Xiaoli Qi, Elise Shen, Yu-Chi Sun, Huizhong W Tao, Wayne Wakemen, Yimin Wang, Shenqin Yao, Jing Yuan, Huiqing Zhan, Muye Zhu, Lydia Ng, Li I Zhang, Byung Kook Lim, Michael Hawrylycz, Hui Gong, James C Gee, Yongsoo Kim, Kwanghun Chung, X William Yang, Hanchuan Peng, Qingming Luo, Partha P Mitra, Anthony M Zador, Hongkui Zeng, Giorgio A Ascoli, Z Josh Huang, Pavel Osten, Julie A Harris, Hong-Wei Dong, “Cellular anatomy of the mouse primary motor cortex”, Nature, 2021      

John W. Hickey*, Elizabeth K. Neumann*, Andrea J. Radtke*, Jeannie M. Camarillo, Rebecca T. Beusche, Alexandre Albanese, Elizabeth McDonough, Julia Hatler, Anne E. Wiblin, Jeremy Fisher, Josh Croteau , Eliza C. Small, Anup Sood, Richard M. Caprioli, R. Michael Angelo, Garry P. Nolan, Kwanghun Chung, Stephen M. Hewitt, Ronald N. Germain, Jeffrey M. Spraggins, Emma Lundberg, Michael P. Snyder, Neil L. Kelleher and Sinem K. Saka†, "Spatial mapping of protein composition and tissue organization: a primer for multiplexed antibody-based imaging", Nature Methods, 2021, DOI: 10.1038/s41592-021-01316-y        

Joha Park*, Sarim Khan*, Dae Hee Yun*, Taeyun Ku, Katherine L. Villa, Jiachen E. Lee, Qiangge Zhang, Juhyuk Park, Guoping Feng, Elly Nedivi, Kwanghun Chung†, "Epitope-preserving magnified analysis of proteome (eMAP)", Science Advances, 2021.      

Seo Woo Choi*, Webster Guan*, Kwanghun Chung†, "Basic Principles of hydrogel-based tissue transformation technologies and their applications", Cell, 2021. DOI:10.1016/j.cell.2021.07.009      

Xin Jin, Zelalem Demere, Karthik Nair, Ahmed Ali, Gino Ferraro, Ted Natoli, Amy Deik, Lia Petronio, Andrew A. Tang, Cong Zhu, Li Wang, Danny Rosenberg, Vamsi Mangena, Jennifer Roth, Kwanghun Chung, Rakesh Jain, Clary Clish, Matthew Vander Heiden, Todd R. Golub†, “A metastasis map of human cancer cell lines”, Nature, 2020  

Varoth Lilascharoen, Eric Hou-Jen Wang, Nam Do, Stefan Carl Pate, Amanda Ngoc Tran, Xiao-Yun Wang, Young-Gyun Park, Kwanghun Chung, Byung Kook Lim†, “Divergent pallidal pathways underlying distinct Parkinsonian behavioral deficits”, Nature Neuroscience, 2020  

Alexandre Albanese*, Justin M. Swaney*, Dae Hee Yun, Nicholas B. Evans, Jenna M. Antonucci, Silvia Velasco, Chang Ho Sohn, Paola Arlotta, Lee Gehrke, Kwanghun Chung†, “Multiscale Hyperdimensional Phenotyping of Intact Human Cerebral Organoids”, Scientific Reports, 2020,      

Taeyun Ku, Webster Guan, Nicholas B. Evans, Chang Ho Sohn, Alexandre Albanese, Joon-Goon Kim, Matthew P. Frosch, Kwanghun Chung†, “Elasticizing tissues for reversible shape transformation and accelerated molecular labeling”, Nature Methods, 2020, DOI: 10.1038/s41592-020-0823-y      

Hiroki Ueda†, Ali Erturk, Kwanghun Chung, Viviana Gradinaru, Alain Chédotal, Philipp Keller, and Pavel Tomancak. “Tissue clearing and its applications in neuroscience", Nature Neuroscience, 2020, DOI:10.1038/s41583-019-0250-1    

Dheeraj S Roy*, Young-Gyun Park*, Sachie K Ogawa*, Jae H Cho, Heejin Choi, Lee Kamensky, Jared Martin, Kwanghun Chung†, Susumu Tonegawa†. "Brain-wide mapping of contextual fear memory engram ensembles supports the dispersed engram complex hypothesis", bioRxiv, 2019, DOI:10.1101/668483    

Dae Hee Yun*, Young-Gyun Park*, Jae Hun Cho*, Lee Kamentsky, Nicholas B. Evans, Alex Albanese, Katherine Xie, Justin Swaney, Chang Ho Sohn, Yuxuan Tian, Qiangge Zhang, Gabi Drummond, Webster Guan, Nicholas DiNapoli, Heejin Choi, Hae-Yoon Jung, Luzdary Ruelas, Guoping Feng, Kwanghun Chung†. "Ultrafast immunostaining of organ-scale tissues for scalable proteomic phenotyping", bioRxiv, 2019, DOI:10.1101/660373    

Justin Swaney*, Lee Kamentsky*, Nicholas B Evans, Katherine Xie, Young-Gyun Park, Gabrielle Drummond, Dae Hee Yun, Kwanghun Chung†. "Scalable image processing techniques for quantitative analysis of volumetric biological images from light-sheet microscopy", bioRxiv, 2019, DOI:10.1101/576595    

Rebecca G Canter*, Wen-Chin Huang*, Heejin Choi*, Jun Wang, Lauren A. Watson, Christine G. Yao, Fatema Abdurrob, Stephanie M. Bousleiman, Ivana Delalle†, Kwanghun Chung†, Li-Huei Tsai† "3D Mapping Reveals Network-specific Amyloid Progression and Subcortical Susceptibility", Communications Biology, 2019, DOI:10.1038/s42003-019-0599-8    

Anthony J. Martorell, Abigail L. Paulson, Ho-Jun Suk, Fatema Abdurrob, Gabrielle T. Drummond, Webster Guan, Jennie Z. Young, David Nam-Woo Kim, Oleg Kritskiy, Scarlett J. Barker, Vamsi Mangena, Stephanie M. Prince, Emery N. Brown, Kwanghun Chung, Edward S. Boyden, Annabelle C. Singer, Li-Huei Tsai. "Multi-sensory Gamma Stimulation Ameliorates Alzheimer’s-Associated Pathology and Improves Cognition", Cell, 2019, 2,256-271. DOI:10.1016/j.cell.2019.02.014        

Young-Gyun Park*, Chang Ho Sohn*, Ritchie Chen*, Margaret McCue, Dae Hee Yun, Gabrielle T. Drummond, Taeyun Ku, Nicholas B. Evans, Hayeon Caitlyn Oak, Wendy Trieu, Heejin Choi, Xin Jin, Varoth Lilascharoen, Ji Wang, Matthias C. Truttmann, Helena W. Qi, Hidde L. Ploegh, Todd R. Golub, Shih-Chi Chen, Matthew P. Frosch, Heather J. Kulik, Byung Kook Lim, and Kwanghun Chung^†. "Protection of tissue physicochemical properties using polyfunctional crosslinkers", Nature Biotechnology, 2019, DOI: 10.1038/nbt.4281            

Tomoyuki Mano*, Alexandre Albanese*, Hans-Ulrich Dodt., Ali Erturk, Viviana Gradinaru, Jennifer B. Treweek, Atsushi Miyawaki, Kwanghun Chung^†, and Hiroki R. Ueda^†. "Whole-Brain Analysis of Cells and Circuits by Tissue Clearing and Light-Sheet Microscopy", The Journal of Neuroscience, 2018, DOI: 10.1523/JNEUROSCI.1677-18.2018

Mark Hernandez, Adam Brewster, Larry Thul, Brian A. Telfer, Arjun Majumdar, Heejin Choi, Taeyun Ku, Kwanghun Chung, Laura J. Brattain. “Learning-based long-range axon tracing in dense scenes”, IEEE International Symposium on Biomedical Imaging, 2018, DOI: 10.1109/ISBI.2018.8363875    

Feng-Ju Weng, Rodrigo I. Garcia, Stefano Lutzu, Karina Alviña, Yuxiang Zhang, Margaret Dushko, Taeyun Ku, Khaled Zemoura, David Rich, Dario Garcia-Dominguez, Matthew Hung, Tushar D. Yelhekar, Andreas Toft Sørensen, Weifeng Xu, Kwanghun Chung, Pablo E. Castillo, Yingxi Lin. "Npas4 Is a Critical Regulator of Learning-Induced Plasticity at Mossy Fiber-CA3 Synapses during Contextual Memory Formation", Neuron, 2018, DOI: 10.1016/j.neuron.2018.01.026  

Laura J. Brattain, Mihnea Bulugioiu, Adam Brewster, Mark Hernandes, Heejin Choi, Taeyun Ku, Kwanghun Chung, Vijay Gadepally. “A cloud-based brain connectivity analysis tool”, IEEE High Performance Extreme Computing Conference, 2017  

Laura J. Brattain, Brian A. Telfer, Siddharth Samsi, Taeyun Ku, Heejin Choi, Kwanghun Chung. “Automated dense neuronal fiber tracing and connectivity mapping at cellular level”, IEEE International Symposium on Biomedical Imaging, 2017  

Kwanghun Chung. "A bigger and better picture of clinical samples", Science Translational Medicine, 2017, DOI: 10.1126/scitranslmed.aao4209  

Norman Lippok, Martin Villiger, Alexandre Albanese, Eelco F.J. Meijer, Kwanghun Chung, Timothy P. Padera, Sangeeta N. Bhatia, and Brett E. Bouma. "Depolarization signatures map gold nanorods within biological tissue", Nature Photonics, 2017, DOI: 10.1038/NPHOTON.2017.128  

Norman Lippok, Martin Villigefa-external-linkr, Alexandre Albanese, Eelco F.J. Meijer, Kwanghun Chung, Timothy P. Padera, Sangeeta N. Bhatia, and Brett E. Bouma. "Depolarization signatures map gold nanorods within biological tissue", Nature Photonics, 2017, DOI: 10.1038/NPHOTON.2017.128  

Kelly R. Stevens, Margaret A. Scull, Vyas Ramanan, Chelsea L. Fortin, Ritika R. Chaturvedi, Kristin A. Knouse, Jing W. Xiao, Canny Fung, Teodelinda Mirabella, Amanda X. Chen, Margaret G. McCue, Michael Yang, Heather E. Fleming, Kwanghun Chung, Ype P. de Jong, Christopher S. Chen, Charles M. Rice, Sangeeta N. Bhatia. " In situ expansion of engineered human liver tissue in a mouse model of chronic liver disease", Science Translational Medicine, 2017, 9  

Kwanghun Chung. "Accelerating the production of insulating brain cells", Science Translational Medicine, 2017, DOI: 10.1126/scitranslmed.aan8203  

Kwanghun Chung. "Modeling human brain development", Science Translational Medicine, 2017, DOI: 10.1126/scitranslmed.aan4295  

Kwanghun Chung. "Kill or be killed: The epic battle between Zika virus and cells revealed", Science Translational Medicine, 2017, DOI: 10.1126/scitranslmed.aam9859  

Kwanghun Chung. "Toward off-the-shelf adoptive T cell therapies", Science Translational Medicine, 2017, DOI: 10.1126/scitranslmed.aan2779  

Jian Ren, Heejin Choi, Kwanghun Chung, and Brett E. Bouma. "Label-free volumetric optical imaging of intact murine brains", Scientific Report, 2017, 7, DOI:10.1038/srep46306.  

Magdalena Renner, Madeline A. Lancaster, Shan Bian, Heejin Choi, Taeyun Ku, Angela Peer, Kwanghun Chung, and Juergen A. Knoblich. “Self-organized developmental patterning and differentiation in cerebral organoids”, EMBO J, 2017, doi: 10.15252/embj.201694700.  

Taeyun Ku, Justin Swaney, Jeong-Yoon Park, Alexander Albanese, Evan Murray, Jae Hun Cho, Young-Gyun Park, Vamsi Mangena, Jiapei Chen, and Kwanghun Chung. "Multiplexed and scalable super-resolution imaging of three-dimensional protein localization in size-adjustable tissues", Nature Biotechnology, 2016, doi:10.1038/nbt.3641.        

Alexandre Albanese, Kwanghun Chung. "Neuroimaging: Whole-brain imaging reaches new heights (and lengths)", eLife, 2016, 5:e, 13367.  

Evan Murray, Jae Hun Cho, Daniel Goodwin, Taeyun Ku, Justin Swaney, Sung-Yon Kim, Heejin Choi, Young-Gyun Park, Jeong-Yoon Park, Austin Hubbert, Margaret McCue, Sara Vassallo, Naveed Bakh, Matthew P. Frosch, Van J. Wedeeng, H. Sebastian Seung, and Kwanghun Chung. "Simple, scalable proteomic imaging for high-dimensional profiling of intact systems", Cell, 2015, 163, 6, 1500–1514          

Sung-Yon Kim, Jae Hun Cho, Evan Murray, Naveed Bakh, Heejin Choi, Kimberly Ohn, Luzdary Ruelas, Austin Hubbert, Meg McCue, Sara L. Vassallo, Philipp J. Keller, Kwanghun Chung. "Stochastic electrotransport selectively enhances the transport of highly electromobile molecules", PNAS, 2015, 12, 46, E6274–E6283    

Jitendra S Kanodia, Yoosik Kim, Raju Tomer, Zia Khan, Kwanghun Chung, John D. Storey, Hang Lu, Philipp Keller, and SY Shvartsman, “A computational statistics approach for estimating the spatial range of morphogen gradient”, Development, 2011, 138, 4867-4874.  

Kwanghun Chung*, Mei Zhan*, Jagan Srinivasan, Paul Sternberg, Emily Gong, Frank Schroeder, and Hang Lu, “Microfluidic chamber arrays for whole-organism behavior-based chemical screening”, Lab on a Chip, 2011, 11, 3689-3697.      

Kwanghun Chung*, Catherine A. Rivet*, Melissa Kemp, and Hang Lu, “Imaging single-cell signaling dynamics with a deterministic high-density single-cell trap array”, Analytical Chemistry, 2011, 83, 7044-7052.      

Yoosik Kim, Maria Jose Andreu, Bomyi Lim, Kwanghun Chung, Mark Terayama, Gerardo Jimenez, Celeste A. Berg, Hang Lu and Stanislav Y Shvartsman, “Gene regulation by MAPK substrate competition”, Developmental Cell, 2011, 20, 880-887.    

Kwanghun Chung*, Yoosik Kim*, Jitendra S Kanodia, Emily Gong, SY Shvartsman, and Hang Lu, “A microfluidic array for large-scale ordering and orientation of embryos”, Nature Methods, 2011, 8, 2, 171-176.      

Matthew Crane, Kwanghun Chung, Jeffrey Stirman, and Hang Lu, “Microfludics-enabled phenotyping, imaging, and screening of multicellular organisms”, Lab on a Chip, 2010, 21, 1509-17.  

Kwanghun Chung*, Hyewon Lee*, and Hang Lu, “Multiplex pressure measurement in microsystems using volume displacement of fluorescent particle suspension”, Lab on a Chip, 2009, 9, 3345-3353.  

Kwanghun Chung and Hang Lu, “Automated high-throughput cell microsurgery on-chip”, Lab on a Chip, 2009, 9, 2764-2766.    

Kwanghun Chung*, Jaekyu Cho*, Edward Park, Victor Breedveld, and Hang Lu, “Three-dimensional In Situ Temperature Measurement in Microfluidic System Using Brownian Motion of Nanoparticles”, Analytical Chemistry, 2009, 81, 210-217.  

Matthew M. Crane, Kwanghun Chung, and Hang Lu, “Computer-enhanced high-throughput genetic screens of C. elegans in a microfluidic system”, Lab on a Chip, 2009, 9, 38-40.      

Kwanghun Chung, Matthew M. Crane, Hang Lu, “Automated on-chip rapid microscopy, phenotyping, and sorting of C. elegans”, Nature Methods, 2008, 5, 637-643    

Kwanghun Chung, Juhan Kim, Byung-Kwan Cho, Byoung-Joon Ko, Bum-Yeol Hwang, Byung-Gee Kim “How does dextran sulfate prevent heat induced aggregation of protein?: The mechanism and its limitation as aggregation inhibitor”, BBA-Proteins and Proteomics, 2007, 1774, 249-257.