We are excited to share that our lab’s latest innovations have been featured in MIT News! The article showcases the new CuRVE and eFLASH technologies, which enable ultrafast and uniform protein labeling across tens of millions of densely packed individual cells in fully intact 3D tissues with unprecedented precision and scalability. This breakthrough addresses critical challenges in studying complex biological systems, such as brain tissue and organoids, where dense cellular environments often hinder detailed protein analysis. By integrating advanced molecular engineering, high-resolution imaging, and computational analysis, our approach allows for more accurate characterization of protein distributions in situ. This innovation significantly improves the speed and accuracy of protein visualization, unlocking new possibilities for biological and neuroscience research.
Read the full article on MIT News: MIT method enables ultrafast protein labeling of tens of millions of densely packed cells
Publication in Nature Biotechnology: View the study
Watch the technology in action:
This advancement represents a major step forward in whole-organ protein imaging and provides researchers with a more reliable way to study cellular protein expression in complex biological systems. We look forward to seeing how these technologies will be applied to future discoveries!
For more details, visit MIT News.
